Diagnostic technologies
VTT provides R&D services and upscaling solutions for novel and integrated diagnostics devices in predictive and preventive health care, food safety and environmental monitoring.
Key facts about diagnostic technologies
Accelerated design and development of diagnostic devices through VTT’s unique pilot infrastructure
Low-cost diagnostic devices can help to generate continuous data for clinical decision support and AI
We can tailor antibodies to detect specific molecules such as protein biomarkers, toxins, hormones, vitamins, antibiotics and food contaminants
Our biosensor and wearables group is part of VTT’s Sensing and Integration research area which combines competences in recombinant antibody and assay development, printed and hybrid biosensors, optoelectronics, wearable device design, material science and biotechnology. One of VTT’s key differentiators in diagnostics and wearable device development is the unique pilot manufacturing infrastructure, which allows prototype upscaling studies early on in the development cycle. Key research and development focus areas include:
- Assay development for:
- rapid immunoassays in different diagnostics platforms including FRET, arrays-in-wells, lateral flow assays (LFA)
- nucleic acid assays
- printed electrochemical sensors
- Tailored recombinant antibody development and production:
- antibodies for diagnostic and analytical applications including VTT’s proprietary immune complex antibody technology
- therapeutic antibodies for pre-clinical studies
- discovery of new antibodies from phage display libraries
- production and purification services
- Innovative biosensor platforms and next generation devices in combination with unique and high-value recombinant antibodies
- Highly sensitive and reliable diagnostic instruments and tools for use at home and at POC-settings in different applications fields
- Upscaling and roll-to-roll (R2R) pilot manufacturing of microfluidic devices on several substrates (foil, paper, PDMS)
- Printed sensors and indicators for easy-to-use food and environmental safety tests
Research infrastructure
- PrintoCent Pilot Factory
- Pilot line for roll-to-roll (R2R) PDMS device processing for microfluidic applications and surface functionalization
- Biolab for next generation lateral flow assay (LFA) and microfluidic chip assay and manufacturing development
VTT is part of MedPhab - European Pilot Line for Photonic Medical Devices.
More information
- Wearable sensors detect what’s in your sweat
- Regional and correlative sweat analysis using high-throughput microfluidic sensing patches toward decoding sweat
- New affordable, credit-card-size rapid test to see if you’re fit to drive
Public references & videos related to diagnostic technologies:
- Roll-to-roll manufacturing of integrated immunodetection sensors
- Sweat analytics collaboration with UC Berkeley
- Roll-to-roll upscaling of lab-on-chip devices (Ultraplacad EU project): https://www.youtube.com/watch?v=ZLkYtVlPrV0 and www.ultraplacad.eu
- Immunocomplex antibody technology
- Roll-to-roll fabrication of integrated PDMS–paper microfluidic
- MedPhab Europe’s first Photonics Pilot Line on medical applications
- CADMIM collaboration
See our publications related to diagnostic technologies:
- New pressure sensing elements for FFR coronary catheter
- Integration of a capacitive pressure sensing system into the outer catheter wall for coronary artery FFR measurements
- New MEMS pressure sensor element and concept for coronary catheter
- Ultrathin MEMS pressure sensor and readout ASIC
- SAFTIR - a novel point-of-need diagnostic platform for animal health and food safety
