Advanced bioanalytical methods are essential for product and material development and successful production processes. VTT provides characterisation and quantification services for chemicals, metabolites, and proteins.
Our bioanalytical services can help you develop more efficient production processes whether you operate in the pharmaceutical, biotechnology, or chemistry field.
We use mass spectrometry (MS) and nuclear magnetic resonance (NMR) based analyses of proteins, cellular metabolites and chemical composition.
We determine structures by several methods, including NMR.
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Data-based decision-making with bioanalytics
Advanced bioanalytics provide valuable data that can be used to improve processes or products. It can be utilised in versatile ways in medicine, biotechnology, and chemistry, as well as agriculture and the food industry, especially novel foods.
VTT provides tailored analytics for specific samples, providing information to guide decision-making. Our services are customisable according to your needs.
We specialise in agile, tailor-made analytical solutions based on mass spectrometry (MS) and nuclear magnetic resonance spectroscopy (NMR). We utilise these techniques to characterise and quantify chemical composition, bioactive compounds, or protein modifications in biological matrices. We are highly experienced in analysing cellular metabolites, lipids, carbohydrates as well as proteins and their post-translational modifications.
Here are some examples of questions we have helped our customers with:
- Is the molecular mass of the protein correct compared to the theoretical mass?
- Is the glycan structure of the protein correct compared to the reference protein?
- Are there side products yielded in the biotechnological process? / Could this biotechnological process yield any side products?
- Do our genetic modifications work in the way we intended?
Serving the food industry
In the food industry, the customer often has to provide the authorities with different kinds of samples of their product, including information on what the sample contains and how it compares to the competitor’s product. This happened, for example, to VTT's spin-off company eniferBio, which manufactures fish feed. Test results indicated that the feed was not being properly absorbed by the fish’s metabolism, resulting in sickness in the fish. Our team of bioanalytics researchers analysed the composition of the feed and found that the problem was caused by a certain component in the product.
Success story: VTT’s laboratory-grown coffee experiment
In the autumn of 2021, VTT managed to grow coffee from plant cells. The biotechnological production of coffee began with the establishment of a coffee cell culture in VTT's laboratory. It was then transferred to bioreactors to produce a larger amount of biomass.
After finding a suitable roasting process, the new coffee was found to smell and taste almost like ordinary coffee. Bioanalysis was then used to investigate whether cell coffee has the same aroma compounds as real coffee, whether it contains caffeine, and how the fermentation of plant material affects flavouring substances or protein composition.
Customer story: Dyadic
VTT collaborates with Dyadic inc. in its biological drug and vaccine development and VTT analytics continuously supports this work by analytical characterization of proteins and glycans, mostly by high resolution LC-MS. For more information see for example the press release on the Covid vaccine development: "Dyadic's DYAI-100 COVID-19 Vaccine Study Published in a Leading Peer-Reviewed Scientific Journal"
VTT’s world-class experts in bioanalytics
How to work with us
When it comes to bioanalytical services, there are many ways to utilise our expertise.
Tell us what you want to do, and we will figure out how. No project is too small or too ambitious – we would love to hear from you. After the initial assessment, we might be able to offer some of the options listed below.
Every research case is unique, and we’re happy to tailor our services to your needs. You will get full ownership of the intellectual property rights of any project we undertake together.
We frequently participate in research and development projects with multiple business partners and funding agencies. In cooperative projects, the risk is split between multiple organisations and everyone benefits from the results.
Our networks at your disposal
We are happy to put you in touch with the ideal sparring and development partner.