From food and feed to chemicals, fuels, materials and pharmaceuticals, fermentation processes are opening more sustainable routes to the products society needs. VTT reduces society’s reliance on fossil-based resources by scaling and optimising a broad range of tailored solutions for bioprocesses and exploitation of different organisms.
Key facts
Turn your new process into a validated, optimised and industrially viable bioproduction solution.
Reduce investment risk by accessing pilot-scale equipment and expertise.
More than 80 fermenters with real-time process monitoring and leading downstream processing equipment at your disposal.
Bioprocess development enables clean and resource-efficient production
Bioprocess development responds to the urgent need for cleaner, more resource-efficient production. It turns renewable raw materials and waste streams into scalable solutions for food, chemicals, materials, fuels and pharmaceuticals.
With the right know-how, renewable raw materials can be economically converted into valuable intermediates and products. Bioprocess development helps you design, test and refine a financially viable manufacturing process for developing sustainable organic acids, vaccines, proteins, polymer precursors, plastics, chemicals and fuels.
Scale your production from lab to factory faster
The jump from a laboratory to a full-scale production line is a big investment. VTT’s bioprocess development experts reduce the risks of the investment and ensure a safe production process for your solution.
Bioprocess development optimises the production process to find the most economical way of producing a product. By scaling the production incrementally towards larger reactors, you can make the production more sustainable and energy efficient.
VTT supports the full bioprocess development value chain, from raw material pre-treatment to fermentation, downstream separation and purification – from small laboratory scale all the way to pilot scale.
Valuable process development expertise and resources at your disposal
VTT’s well-equipped bioprocess facilities include more than 80 fermenters, ranging from less than 200 mL to 1,200 L volume. The reactors are connected to various online measurements for real-time process monitoring and control. Several parameters can be measured from offline samples (such as cell dry weight, sugars, organic acids and other metabolites) to fully characterise the fermentation process.
To support efficient scale-up and process optimisation, the facilities also include a customisable advanced downstream processing line with:
- centrifuges
- a drum filter
- a continuous separator
- a press filter
- pressure-based cell lysis
- micro- and ultra-filtration units
- spray and freeze dryers.
Our experts have successfully developed processes ranging from the most surprising raw materials, such as bacteria, yeasts, fungi, and algae and plant cells, to the most extravagant products. We have hands-on experience with both bioprocess development consulting and bioprocessing.
Related infrastructure
VTT has leading expertise in the following areas
- Bioprocess development and modelling
- Fermentations and their control (e.g. feeding strategies and continuous cultures)
- Real-time process monitoring (e.g. Raman spectrometry, in-line microscopy)
- Pilot scale downstream processing (e.g. cell separation, ultrafiltration, drying)
- Automated cultivations with two Sartorius ambr250 24-vessel bioreactor systems
- Microbial physiology
- Fungal protein production
- Biorefinery, biofuels and biochemicals.
Contact us here!
Project cases
Egg white protein production technology without chickens awarded by EARTO
VTT developed a safe, environmentally sustainable and cost-effective method for mass production of high value proteins, such as egg white, without using animals.
New VTT-based startup company eniferBio produces protein from biorefinery by-products
eniferBio has developed a new and sustainable production process for a high-quality fish feed ingredient and recently received funding for its solution from two funds.
VTT Industrial Biotechnology: Microtiter to Pilot Scale
VTT Industrial Biotechnology: Pilot facility
VTT’s bioprocess development specialists
Get to know our experts and explore our equipment.
